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- Juan Fernando Duque Osorio, Adalberto Sánchez, Leonardo Fierro, Silverio Garzón, Rafael Santiago Castaño, VENENOS DE SERPIENTES Y MOLÉCULAS ANTIVENENO , Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales: Vol. 31 Núm. 118 (2007)
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No se cuenta con descripciones de la estructura interna del MC del único primate simiiforme (antropoideo) nocturno, Aotus. Dado que el MC es importante en la regulación del sueño, se evaluó esta estructura en Aotus, con una técnica histológica y otra Inmunohistoquímica. El MC de Aotus y Homo contienen esencialmente los mismos elementos grises y blancos. Con la técnica Inmunohistoquímica para Serotonina, se encontró un posible núcleo serotoninérgico nuevo (NN?) para el MC de Aotus, que no ha sido descrito en el MC humano. Teniendo en cuenta las relaciones que tendría el NN? con estructuras componentes de los CRS a este núcleo como un posible componente adicional de dichos circuitos, logrando, en mamíferos nocturnos como Aotus, que por un lado la influencia excitadora de la luz del día, tenga un efecto inhibidor sobre el Tálamo y la Corteza Cerebral, y por otro lado haciendo que la influencia inhibidora de la falta de luz durante la noche, tenga el efecto contrario. Dado que, para refugiarse de la predación y relajar competencia con los reptiles dominantes (arcosaurios: dinosaurios) del período Triásico, los primeros mamíferos eran nocturnos, se propone la posibilidad de que el NN? sea plesiomórfico para los mamíferos y que en mamíferos diurnos, el desarrollo de este núcleo putativo se reprima. La existencia del NN? debe ser confirmada con otros estudios.
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