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Se establece una comparación entre la coccidioidomicosis y la paracoccidioidomicosis, afecciones que se informan solo en el continente americano y que son causadas por los hongos dimórficos, Coccidioides immitis y Paracoccidioides brasiliensis; se anotan las semejanzas en las presentaciones clínicas de ambas micosis contrastando las diferencias morfológicas y de reproducción de los agentes, así como sus divergentes aspectos eco-epidemiológicos. Se destacan las notables diferencias en las zonas endémicas, señalando que la coccidioidomicosis ocurre únicamente en áreas desérticas del Nuevo Mundo, mientras que la paracoccidioidomicosis, inexistente en América del Norte, se distribuye irregularmente entre México y Argentina con una marcada predilección por zonas boscosas y ricas en corrientes de agua.
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