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Se determinó la secuencia completa del ARN genómico del Virus del mosaico común del fríjol (Bean common mosaic virus) cepa NL4 (BCMV-NL4). El genoma viral consta de 10037 nucleótidos excluyendo la cola de poli (A) y contiene una trama de lectura abierta (ORF) de 9666 nucleótidos que codifica una poliproteína de 3222 aminoácidos. La ORF está flanqueada por dos regiones no traducidas (UTR): la 5’UTR de 133 nucleótidos y la 3’UTR de 235 nucleótidos. Análisis comparativos de la poliproteína del BCMV-NL4 con otras especies del género Potyvirus, reveló nueve sitios de clivaje que resultaron en las diez proteínas funcionales características de estos virus. Alineamientos múltiples de las secuencias de nucleótidos del ARN genómico y de aminoácidos de la poliproteína del BCMV-NL4 con las de otros miembros de la familia Potyviridae mostraron una relación estrecha entre el BCMV-NL4 y el BCMV-NL1. Las comparaciones mediante el uso del programa Blast de las secuencias de la proteína de la cápsida (CP) y de la 3’UTR, mostraron una identidad del 100% entre el BCMV-NL4 y la variante mexicana (US6) de esta cepa.
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